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Cancer Stem Cells Stemness Transcription Factors Expression Correlates with Breast Cancer Disease Stage

2 Dec 2012

Abstract excerpt

Cancer stem cell-like cells (CSCs) are cancer cells that have the ability of self-renewal and differentiation into multiple malignant cell types (hierarchy). Thus, can cause relapses and metastasis. CSCs' phenotype is defined by special transcription factors such as Nanog, Oct3/4, Sox2, Nestin, and CD34. The present study aims to determine the change in gene expression of the above markers in correlation with the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 23061814
DOI: 10.2174/157488812804484639

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