Article
Disease modelling using induced pluripotent stem cells: status and prospects.
BioEssays : news and reviews in molecular, cellular and developmental biology - 1 Mar 2013
Pomp Oz, Colman Alan
Abstract excerpt
The ability to convert human somatic cells into induced pluripotent stem cells (iPSCs) is allowing the production of custom-tailored cells for drug discovery and for the study of disease phenotypes at the cellular and molecular level. IPSCs have been derived from patients suffering from a large variety of disorders with different severities. In many cases, disease related phenotypes have been observed in iPSCs or...
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