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Article

Impaired therapeutic capacity of autologous stem cells in a model of type 2 diabetes.

Stem cells translational medicine - 1 Feb 2012

Shin Laura, Peterson Daniel A

Abstract excerpt

Endogenous stem cells in the bone marrow respond to environmental cues and contribute to tissue maintenance and repair. In type 2 diabetes, a multifaceted metabolic disease characterized by insulin resistance and hyperglycemia, major complications are seen in multiple organ systems. To evaluate the effects of this disease on the endogenous stem cell population, we used a type 2 diabetic mouse model (db/db), which...

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Share to Bone Marrow
Share to Cell Survival
Share to Diabetes Mellitus, Type 2

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Mesenchymal Stem Cell Transplantation

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Share to Transplantation, Autologous

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Identifiers

PMID: 23197759
DOI: 10.5966/sctm.2012-0031
PMCID: PMC3659680

Genes

MSC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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