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Article

The endothelial cell secretome as a novel treatment to prime adipose-derived stem cells for improved wound healing in diabetes.

Journal of vascular surgery - 1 Jul 2018

Fromer Marc W, Chang Shaohua, Hagaman Ashleigh L R, Koko Kiavash R, Nolan Ryan S, Zhang Ping, Brown Spencer A, Carpenter Jeffrey P, Caputo Francis J

Abstract excerpt

BACKGROUND: Chronic wounds are a common surgical problem exacerbated by diabetes and ischemia. Although adipose-derived stem cells (ASCs) have shown promise as a wound healing therapy, their function and proliferation are hindered in diabetes. This study examines the ability of the human umbilical vein endothelial cell (HUVEC) secretome to reverse the deleterious effects of high glucose concentrations on ASCs...

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Source

Identifiers

PMID: 28760584
DOI: 10.1016/j.jvs.2017.05.094

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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