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Article

Joint estimation of copy number variation and reference intensities on multiple DNA arrays using GADA.

Bioinformatics (Oxford, England) - 15 May 2009

Pique-Regi Roger, Ortega Antonio, Asgharzadeh Shahab

Abstract excerpt

MOTIVATION: The complexity of a large number of recently discovered copy number polymorphisms is much higher than initially thought, thus making it more difficult to detect them in the presence of significant measurement noise. In this scenario, separate normalization and segmentation is prone to lead to many false detections of changes in copy number. New approaches capable of jointly modeling the copy number...

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Identifiers

PMID: 19276152
DOI: 10.1093/bioinformatics/btp119
PMCID: PMC2732310

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

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