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Article

A Hidden Markov Model to estimate population mixture and allelic copy-numbers in cancers using Affymetrix SNP arrays.

BMC bioinformatics - 9 Nov 2007

Lamy Philippe, Andersen Claus L, Dyrskjot Lars, Torring Niels, Wiuf Carsten

Abstract excerpt

BACKGROUND: Affymetrix SNP arrays can interrogate thousands of SNPs at the same time. This allows us to look at the genomic content of cancer cells and to investigate the underlying events leading to cancer. Genomic copy-numbers are today routinely derived from SNP array data, but the proposed algorithms for this task most often disregard the genotype information available from germline cells in paired...

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Identifiers

PMID: 17996079
DOI: 10.1186/1471-2105-8-434
PMCID: PMC2206057

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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