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Article

Thymic stromal lymphopoietin gene promoter polymorphisms and expression levels in Graves' disease and Graves' ophthalmopathy.

BMC medical genetics - 30 Nov 2012

Tsai Kun-Hsi, Tsai Fuu-Jen, Lin Hui-Ju, Lin Hung-Jung, Liu Yu-Huei, Liao Wen-Ling, Wan Lei

Abstract excerpt

BACKGROUND: Graves disease (GD) is an organ-specific autoimmune disease characterized by hyperthyroidism, diffuse goiter, autoantibodies against thyroid-specific antigens, and dermopathy. Studies of GD have demonstrated the importance of the Th2 and Th17 immune responses in mediating disease progression. In the present study, we investigated the role of a Th2 cytokine, thymic stromal lymphopoietin (TSLP), in GD...

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Identifiers

PMID: 23194010
DOI: 10.1186/1471-2350-13-116
PMCID: PMC3582428

Genes

TSLP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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