Article
PRDM9 gene polymorphism may not be associated with defective spermatogenesis in the Chinese Han population.
Systems biology in reproductive medicine - 1 Feb 2013
He Xiao-Jin, Ruan Jian, Du Wei-Dong, Cao Yun-Xia, Chen Gang, Zuo Xian-Bo, Peng Yu-Wan, Wu Huan, Song Bing, Zhang Xue-Jun
Abstract excerpt
PRDM9 is essential for the progression through early meiotic prophase, including double strand break repair, homologous chromosome pairing, and sex body formation during spermatogenesis. In order to evaluate the association of the PRDM9 gene variants with defective spermatogenesis in the Chinese Han population, we assessed two single nucleotide polymorphisms (SNPs) in the PRDM9 gene (rs1874165 and rs2973631)...
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