Article
Association of USP26 haplotypes in men in Taiwan, China with severe spermatogenic defect.
Asian journal of andrology - 1 Nov 2008
Lee I-Wen, Kuan Long-Ching, Lin Chien-Hung, Pan Hsien-An, Hsu Chao-Chin, Tsai Yung-Chieh, Kuo Pao-Lin, Teng Yen-Ni
Abstract excerpt
AIM: To complete comprehensive haplotype analysis of USP26 for both fertile and infertile men. METHODS: Two hundred infertile men with severe oligospermia or non-obstructive azoospermia were subjected to sequence analysis for the entire coding sequences of the USP26 gene. Two hundred men with proven fertility were genotyped by primer extension methods. Allele/genotype frequencies, linkage disequilibrium (LD)...
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