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Article

Association of a TDRD1 variant with spermatogenic failure susceptibility in the Han Chinese.

Journal of assisted reproduction and genetics - 1 Aug 2016

Zhu Xiao-Bin, Lu Jian-Qi, Zhi Er-Lei, Zhu Yong, Zou Sha-Sha, Zhu Zi-Jue, Zhang Feng, Li Zheng

Abstract excerpt

PURPOSE: Piwi-interacting RNAs (piRNAs) are a broad group of noncoding small RNAs that have important biological functions in germline cells and can maintain genome integrity via silencing of retrotransposons. In this study, we aimed to explore the associations between genetic variants of important genes involved in piRNA biogenesis and male infertility with spermatogenic impairment. METHODS: To this end, five...

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Source

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Identifiers

PMID: 27233649
DOI: 10.1007/s10815-016-0738-9
PMCID: PMC4974230

Genes

TDRD1
PIWIL1
TDRD9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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