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Article

Investigation of piwi-interacting RNA pathway genes role in idiopathic non-obstructive azoospermia.

Scientific reports - 9 Jan 2018

Kamaliyan Zeeba, Pouriamanesh Sara, Soosanabadi Mohsen, Gholami Milad, Mirfakhraie Reza

Abstract excerpt

Genes involved in piwi-interacting RNAs (piRNAs) pathway have an essential role in spermatogenesis. HIWI and TDRD proteins are critical for piRNA biogenesis and function. Therefore, Mutations and polymorphisms in HIWI and TDRD genes may play role in male infertility. The aim of the present study was to investigate the role of HIWI2 rs508485 (T>C) and HIWI3 rs11703684 (C>T) polymorphisms and mutational analysis of...

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Identifiers

PMID: 29317647
DOI: 10.1038/s41598-017-17518-4
PMCID: PMC5760646

Genes

TDRD5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Investigation of piwi-interacting RNA pathway genes role in idiopathic non-obstructive azoospermia.PMID 29317647Read ↗

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