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Article

Genetic variants in meiotic program initiation pathway genes are associated with spermatogenic impairment in a Han Chinese population.

PloS one - 1 Jan 2013

Lu Chuncheng, Xu Miaofei, Wang Ying, Qin Yufeng, Du Guizhen, Wu Wei, Han Xiumei, Ji Chao, Yang Yanli, Gu Aihua, Xia Yankai, Song Ling, Wang Shoulin, Wang Xinru

Abstract excerpt

BACKGROUND: The meiotic program initiation pathway genes (CYP26B1, NANOS1 and STRA8) have been proposed to play key roles in spermatogenesis. OBJECTIVE: To elucidate the exact role of the genetic variants of the meiosis initiation genes in spermatogenesis, we genotyped the potential functional genetic variants of CYP26B1, NANOS1 and STRA8 genes, and evaluated their effects on spermatogenesis in our study...

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Share to Adaptor Proteins, Signal Transducing
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cytochrome P-450 Enzyme System

Share to Infertility, Male

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Identifiers

PMID: 23320086
DOI: 10.1371/journal.pone.0053443
PMCID: PMC3540065

Genes

STRA8
NANOS1

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