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Article

A new target for gold(I) compounds: glutathione-S-transferase inhibition by auranofin.

Journal of inorganic biochemistry - 1 Feb 2013

De Luca Anastasia, Hartinger Christian G, Dyson Paul J, Lo Bello Mario, Casini Angela

Abstract excerpt

Nowadays, gold compounds occupy a relevant position constituting a promising class of experimental anticancer metallodrugs. Several research efforts have been devoted to the investigations of the pharmacological properties of gold(I) complexes bearing phosphine ligands, such as the antiarthritic drug auranofin, that has also been shown to produce anticancer effects in vitro. In spite of the numerous studies that...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 23183361
DOI: 10.1016/j.jinorgbio.2012.08.006

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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