Article
Protective role of Interleukin 27 (IL-27) gene polymorphisms in patients with ulcerative colitis.
Immunology letters - 1 Apr 2016
Yamamoto-Furusho Jesús K, Posadas-Sánchez Rosalinda, Alvarez-León Edith, Vargas-Alarcón Gilberto
Abstract excerpt
Ulcerative colitis (UC) is a chronic condition of unknown etiology and a polygenic disease. The interleukin 27 (IL-27) have been implicated in the pathogenesis of several autoimmune diseases including inflammatory bowel disease. Several polymorphisms of IL-27 have been associated with several types of cancer and immune disorders. The aim of the present study was to evaluate the association between IL-27 gene...
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