Article
IL-23 receptor gene rs7517847 and rs1004819 SNPs in ulcerative colitis.
Iranian journal of immunology : IJI - 1 Jun 2012
Hayatbakhsh Mohammad Mahdi, Zahedi Mohammad Javad, Shafiepour Mohsen, Nikpoor Amin Reza, Mohammadi Mojgan
Abstract excerpt
BACKGROUND: Crohn's disease (CD) and ulcerative colitis (UC) are two major clinical presentations of inflammatory bowel disease (IBD). Many novel candidate genes have been found to be associated with increased risk for IBD. Recently IL-23 receptor gene is identified as an IBD associated gene in genome-wide studies. OBJECTIVE: To ascertain whether rs7517847 and rs1004819 SNPs in the IL-23 receptor gene are...
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