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Article

Precision Medicine in Systemic Mastocytosis.

Medicina (Kaunas, Lithuania) - 20 Oct 2021

Nicolosi Maura, Patriarca Andrea, Andorno Annalisa, Mahmoud Abdurraouf Mokhtar, Gennari Alessandra, Boldorini Renzo, Gaidano Gianluca, Crisà Elena

Abstract excerpt

Mastocytosis is a rare hematological neoplasm characterized by the proliferation of abnormal clonal mast cells (MCs) in different cutaneous and extracutaneous organs. Its diagnosis is based on well-defined major and minor criteria, including the pathognomonic dense infiltrate of MCs detected in bone marrow (BM), elevated serum tryptase level, abnormal MCs CD25 expression, and the identification of KIT D816V...

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Identifiers

PMID: 34833353
DOI: 10.3390/medicina57111135
PMCID: PMC8623914

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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