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Article

Analysis of 2'-O-methylated nucleosides and pseudouridines in ribosomal RNAs using DNAzymes.

Analytical biochemistry - 1 Feb 2007

Buchhaupt Markus, Peifer Christian, Entian Karl-Dieter

Abstract excerpt

Ribosomal RNAs (rRNAs) contain a large number of posttranscriptionally modified nucleosides, the physiological function of which is still unclear. The great majority of modifications in eukaryotes and archaea are 2'-O-ribose methylated nucleosides and pseudouridines. The current methods to identify rRNA modifications are difficult to perform and need expensive reagents. Here we report an easy method to detect...

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Identifiers

PMID: 17181990
DOI: 10.1016/j.ab.2006.11.001

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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