Article
The relationship between long-range chromatin occupancy and polymerization of the Drosophila ETS family transcriptional repressor Yan.
Genetics - 1 Feb 2013
Webber Jemma L, Zhang Jie, Cote Lauren, Vivekanand Pavithra, Ni Xiaochun, Zhou Jie, Nègre Nicolas, Carthew Richard W, White Kevin P, Rebay Ilaria
Abstract excerpt
ETS family transcription factors are evolutionarily conserved downstream effectors of Ras/MAPK signaling with critical roles in development and cancer. In Drosophila, the ETS repressor Yan regulates cell proliferation and differentiation in a variety of tissues; however, the mechanisms of Yan-mediated repression are not well understood and only a few direct target genes have been identified. Yan, like its human...
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