Article
Promoter hypomethylation of TIMP3 is associated with pre-eclampsia in a Chinese population.
Molecular human reproduction - 1 Mar 2013
Xiang Yuqian, Zhang Xiaojing, Li Qiaoli, Xu Jiawei, Zhou Xinyao, Wang Teng, Xing Qinghe, Liu Yun, Wang Lei, He Lin, Zhao Xinzhi
Abstract excerpt
A study by Yuen RK, Penaherrera MS, von Dadelszen P, McFadden DE, Robinson WP. DNA methylation profiling of human placentas reveals promoter hypomethylation of multiple genes in early-onset preeclampsia. Eur J Hum Genet 2010;18:1006-1012 based on a Canadian population found the tissue inhibitor of the metalloproteinase 3 (TIMP3) gene to be hypomethylated in pre-eclampsia (PE) placentas and to be a potential...
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