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Article

Identification of novel functional sequence variants in the gene for peptidase inhibitor 3.

BMC medical genetics - 23 May 2006

Chowdhury Mahboob A, Kuivaniemi Helena, Romero Roberto, Edwin Samuel, Chaiworapongsa Tinnakorn, Tromp Gerard

Abstract excerpt

BACKGROUND: Peptidase inhibitor 3 (PI3) inhibits neutrophil elastase and proteinase-3, and has a potential role in skin and lung diseases as well as in cancer. Genome-wide expression profiling of chorioamniotic membranes revealed decreased expression of PI3 in women with preterm premature rupture of membranes. To elucidate the molecular mechanisms contributing to the decreased expression in amniotic membranes,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 16719916
DOI: 10.1186/1471-2350-7-49
PMCID: PMC1508140

Genes

MAF
GATA1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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