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Article

Analysis of gene alterations of mitochondrial DNA D-loop regions to determine breast cancer clonality.

British journal of cancer - 4 Dec 2012

Masuda S, Kadowaki T, Kumaki N, Tang X, Tokuda Y, Yoshimura S, Takekoshi S, Osamura R Y

Abstract excerpt

BACKGROUND: It has been a challenge to determine breast cancer clonality accurately. The aim of the present study was to assess methods using formalin-fixed paraffin-embedded (FFPE) tissue to differentiate new primary tumours from true recurrences that are associated with poorer prognoses and often require more aggressive treatment. METHODS: We investigated the novel method of analysing gene alterations of...

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Identifiers

PMID: 23169290
DOI: 10.1038/bjc.2012.505
PMCID: PMC3516690

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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