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Article

Integrated copy number and gene expression analysis detects a CREB1 association with Alzheimer's disease.

Translational psychiatry - 20 Nov 2012

Li Y, Shaw C A, Sheffer I, Sule N, Powell S Z, Dawson B, Zaidi S N Y, Bucasas K L, Lupski J R, Wilhelmsen K C, Doody R, Szigeti K

Abstract excerpt

Genetic variation, both single-nucleotide variations and copy number variations (CNV), contribute to changes in gene expression. In some cases these variations are meaningfully correlated with disease states. We hypothesized that in a genetically heterogeneous disorder such as sporadic Alzheimer'...

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Identifiers

PMID: 23168992
DOI: 10.1038/tp.2012.119
PMCID: PMC3565761

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PAX6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23168992-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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