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Article

Searching for new genetic risk factors for neuropsychiatric disorders in expression databases.

Journal of molecular neuroscience : MN - 1 May 2010

de Souza Manuela Barbosa Rodrigues, de Lemos Roberta Rodrigues, da Cunha José Eriton Gomes, de Lima Filho José Luiz, de Oliveira João Ricardo Mendes

Abstract excerpt

Genetic variations might contribute to differences in protein activities and gene expression levels observed in complex genetic traits, like neuropsychiatric disease. This finding motivated the development of original approaches using expression studies to guide the finding of new genetic variations. We extended this approach to new genes selected from microarrays studies of brain samples of patients with...

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PMID: 20084552
DOI: 10.1007/s12031-009-9321-5

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