Article
In silico identification of new genetic variations as potential risk factors for Alzheimer's disease in a microarray-oriented simulation.
Journal of molecular neuroscience : MN - 1 Sept 2009
Lemos R R, Castelletti C H, Lima Filho J L, Marques E T, Oliveira J R M
Abstract excerpt
Genomic and proteomic studies of neurodegenerative disorders require complementary approaches to integrate the massive amount of data generated in high throughput experimental procedures. We propose a Bioinformatics pipeline in which expression studies guide the selection of candidate genes that should be screened for potential new genetic variations from a public expressed site tags (ESTs) database. Motivated by...
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