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Article

Analysis of copy number variation in Alzheimer's disease: the NIALOAD/ NCRAD Family Study.

Current Alzheimer research - 1 Sept 2012

Swaminathan Shanker, Shen Li, Kim Sungeun, Inlow Mark, West John D, Faber Kelley M, Foroud Tatiana, Mayeux Richard, Saykin Andrew J

Abstract excerpt

Copy number variants (CNVs) are DNA regions that have gains (duplications) or losses (deletions) of genetic material. CNVs may encompass a single gene or multiple genes and can affect their function. They are hypothesized to play an important role in certain diseases. We previously examined the role of CNVs in late-onset Alzheimer's disease (AD) and mild cognitive impairment (MCI) using participants from the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 22486522
DOI: 10.2174/156720512802455331
PMCID: PMC3500615

Genes

ATXN1
ERBB4
GSTT1
NRXN1
RELN

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