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Article

Polymorphisms in ERCC1 and XPF genes and risk of gastric cancer in an eastern Chinese population.

PloS one - 1 Jan 2012

He Jing, Xu Yu, Qiu Li-Xin, Li Jin, Zhou Xiao-Yan, Sun Meng-Hong, Wang Jiu-Cun, Yang Ya-Jun, Jin Li, Wei Qing-Yi, Wang Yanong

Abstract excerpt

BACKGROUND: Inherited functional single nucleotide polymorphisms (SNPs) in DNA repair genes may alter DNA repair capacity and thus contribute to cancer risk. METHODS: Three ERCC1 functional SNPs (rs2298881C>A, rs3212986C>A and rs11615G>A) and two XPF/ERCC4 functional SNPs (rs2276466C>G and rs6498486A>C) were genotyped for 1125 gastric adenocarcinoma cases and 1196 cancer-free controls by Taqman assays. Odds...

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Identifiers

PMID: 23166636
DOI: 10.1371/journal.pone.0049308
PMCID: PMC3499547

Genes

ERCC1
ERCC4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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