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Article

Association of ERCC1 and ERCC2 polymorphisms with colorectal cancer risk in a Chinese population.

Scientific reports - 17 Feb 2014

Ni Min, Zhang Wei-zhong, Qiu Jin-rong, Liu Fei, Li Min, Zhang Ya-jie, Liu Qing, Bai Jin

Abstract excerpt

The ERCC1 and ERCC2 genes are important in repairing DNA damage and genomic instability, and are involved in the nucleotide excision repair pathway. We hypothesized that single nucleotide polymorphisms (SNPs) in ERCC1 and ERCC2 are associated with the risk of colorectal cancer in a Chinese population. To test this hypothesis, we genotyped four functional SNPs (ERCC1 Asn118Asn, C8092A, ERCC2 Asp312Asn, and...

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Source

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Identifiers

PMID: 24531312
DOI: 10.1038/srep04112
PMCID: PMC3925949

Genes

ERCC1
ERCC2

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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