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Article

Characterization of myelin pathology in the hippocampal complex of a transgenic mouse model of Alzheimer's disease.

Current Alzheimer research - 1 Jan 2013

Schmued Larry C, Raymick James, Paule Merle G, Dumas Melanie, Sarkar Sumit

Abstract excerpt

We have characterized the myelin changes observed within the hippocampal complex (HC) of a transgenic (Tg) mouse model of Alzheimer's disease (AD). Individual myelinated fibers were labeled with Black-Gold II while amyloid plaques were labeled with either Congo Red or Pan-A-beta immunofluoresence. Myelinated fibers were never seen passing through amyloid plaques in any region, while conspicuous myelin pathology...

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Source

Identifiers

PMID: 23157338
DOI: 10.2174/1567205011310010005

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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