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Article

An optimum projection and noise reduction approach for detecting rare and common variants associated with complex diseases.

Human heredity - 1 Jan 2012

Turkmen Asuman, Lin Shili

Abstract excerpt

BACKGROUND: Despite the thrilling advances in identifying gene variants that inﬂuence common diseases, most of the heritable risk for many common diseases still remains unidentified. One of the possible reasons for this missing heritability is that the genome-wide association study (GWAS) approaches have been focusing on common rather than rare single nucleotide variants (SNVs). Consequently, there is currently a...

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PMID: 23154579
DOI: 10.1159/000343797

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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