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Article

LDx: estimation of linkage disequilibrium from high-throughput pooled resequencing data.

PloS one - 1 Jan 2012

Feder Alison F, Petrov Dmitri A, Bergland Alan O

Abstract excerpt

High-throughput pooled resequencing offers significant potential for whole genome population sequencing. However, its main drawback is the loss of haplotype information. In order to regain some of this information, we present LDx, a computational tool for estimating linkage disequilibrium (LD) from pooled resequencing data. LDx uses an approximate maximum likelihood approach to estimate LD (r(2)) between pairs of...

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Identifiers

PMID: 23152785
DOI: 10.1371/journal.pone.0048588
PMCID: PMC3494690

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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