Article
Human T-cells directed to seasonal influenza A virus cross-react with 2009 pandemic influenza A (H1N1) and swine-origin triple-reassortant H3N2 influenza viruses.
The Journal of general virology - 1 Mar 2013
Hillaire Marine L B, Vogelzang-van Trierum Stella E, Kreijtz Joost H C M, de Mutsert Gerrie, Fouchier Ron A M, Osterhaus Albert D M E, Rimmelzwaan Guus F
Abstract excerpt
Virus-specific CD8(+) T-cells contribute to protective immunity against influenza A virus (IAV) infections. As the majority of these cells are directed to conserved viral proteins, they may afford protection against IAVs of various subtypes. The present study assessed the cross-reactivity of human CD8(+) T-lymphocytes, induced by infection with seasonal A (H1N1) or A (H3N2) influenza virus, with 2009 pandemic...
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