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Development of Cross-Protective Influenza A Vaccines Based on Cellular Responses

15 May 2015

Abstract excerpt

Seasonal influenza vaccines provide protection against matching influenza A virus (IAV) strains mainly through the induction of neutralizing serum IgG antibodies. However, these antibodies fail to confer a protective effect against mismatched IAV. This lack of efficacy against heterologous influenza strains has spurred the vaccine development community to look for other influenza vaccine concepts, which have the...

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PMID: 26029218
DOI: 10.3389/fimmu.2015.00237

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