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Article

Broad RNA Interference–Mediated Antiviral Immunity and Virus-Specific Inducible Responses in <i>Drosophila</i>

20 Dec 2012

Abstract excerpt

The fruit fly Drosophila melanogaster is a good model to unravel the molecular mechanisms of innate immunity and has led to some important discoveries about the sensing and signaling of microbial infections. The response of Drosophila to virus infections remains poorly characterized and appears to involve two facets. On the one hand, RNA interference involves the recognition and processing of dsRNA into small...

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PMID: 23255357
DOI: 10.4049/jimmunol.1102486

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