Molecular characterisation of cell line models for triple-negative breast cancers

Abstract excerpt

BACKGROUND: Triple-negative breast cancers (BC) represent a heterogeneous subtype of BCs, generally associated with an aggressive clinical course and where targeted therapies are currently limited. Target validation studies for all BC subtypes have largely employed established BC cell lines, which have proven to be effective tools for drug discovery. RESULTS: Given the lines of evidence suggesting that BC cell...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Barrier Structure and Function Studies
• Share to Breast Cancer Treatment Studies
• Share to HER2/EGFR in Cancer Research