Article
Triple-negative breast cancer and the need for new therapeutic targets.
The American journal of pathology - 1 Oct 2013
Engebraaten Olav, Vollan Hans Kristian Moen, Børresen-Dale Anne-Lise
Abstract excerpt
Triple-negative breast cancers (TNBCs) are a diverse and heterogeneous group of tumors that by definition lack estrogen and progesterone receptors and amplification of the HER2 gene. The majority of the tumors classified as TNBCs are highly malignant, and only a subgroup responds to conventional chemotherapy with a favorable prognosis. Results from decades of research have identified important molecular...
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