Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Common single-nucleotide polymorphisms in the estrogen receptor β promoter are associated with colorectal cancer survival in postmenopausal women.

Cancer research - 15 Jan 2013

Passarelli Michael N, Phipps Amanda I, Potter John D, Makar Karen W, Coghill Anna E, Wernli Karen J, White Emily, Chan Andrew T, Hutter Carolyn M, Peters Ulrike, Newcomb Polly A

Abstract excerpt

Loss of estrogen receptor β (ERβ) expression in the gut is associated with colorectal cancer (CRC) initiation and progression. Germline single-nucleotide polymorphisms (SNP) in genes for the sex-steroid hormone receptors are not strongly associated with CRC risk; however, these SNPs have not previously been evaluated in relation to survival after diagnosis. We enrolled 729 women, ages 50 to 74, diagnosed with...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to Colorectal Neoplasms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Disease Progression

Share to Estrogen Receptor beta

Share to Genetic Predisposition to Disease

Share to Polymorphism, Single Nucleotide

Share to Postmenopause

Share to Promoter Regions, Genetic

Source

Open in PubMed Open full text

Identifiers

PMID: 23149914
DOI: 10.1158/0008-5472.CAN-12-2484
PMCID: PMC3588850

Genes

ESR2
PGR
ESR1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Common single-nucleotide polymorphisms in the estrogen receptor β promoter are associated with colorectal cancer survival in postmenopausal women.PMID 23149914Read ↗

Association of estrogen receptor beta variants and serum levels of estradiol with risk of colorectal cancer: a case control study.Semantic proximity Read ↗

Repeat polymorphisms in ESR2 and AR and colorectal cancer risk and prognosis: results from a German population-based case-control study.Semantic proximity Read ↗

Association of the Estrogen Receptor 1 Polymorphisms rs2046210 and rs9383590 with the Risk, Age at Onset and Prognosis of Breast Cancer.Semantic proximity Read ↗

Estrogen receptor-beta genetic variations and overall survival in patients with locally advanced gastric cancer.Semantic proximity Read ↗

Estrogen receptor-β gene polymorphism and colorectal cancer risk: effect modified by body mass index and isoflavone intake.Semantic proximity Read ↗

Association of genetic polymorphisms in ESR2, HSD17B1, ABCB1, and SHBG genes with colorectal cancer risk.Semantic proximity Read ↗

Colorectal cancer risk associated with hormone use varies by expression of estrogen receptor-β.Semantic proximity Read ↗

Genome-wide DNA methylation differences according to oestrogen receptor beta status in colorectal cancerSemantic proximity Read ↗

Oestrogen receptor-β CA repeat polymorphism is associated with incidence of colorectal cancer among females.Semantic proximity Read ↗

A systematic review of the relationship between polymorphic sites in the estrogen receptor-beta (ESR2) gene and breast cancer risk.Semantic proximity Read ↗

Sex differences in epidemiological, clinical and pathological characteristics of colorectal cancer.Semantic proximity Read ↗

Estrogen receptor polymorphisms and the risk of endometrial cancer.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.