Article
Oestrogen receptor-β CA repeat polymorphism is associated with incidence of colorectal cancer among females.
Histopathology - 1 Aug 2011
Honma Naoko, Arai Tomio, Takubo Kaiyo, Younes Mamoun, Tanaka Noriko, Mieno Makiko Naka, Tamura Kohei, Ikeda Shinobu, Sawabe Motoji, Muramatsu Masaaki
Abstract excerpt
AIMS: Increasing evidence suggests an association between oestrogens and colorectal cancer. Oestrogen receptor beta, ER-β, putatively plays a pathobiological role in colorectal cancer as colorectal epithelial cells frequently express ER-β. The aim was to elucidate the association of the dinucleotide (CA) repeat polymorphism of the ER-β gene (ESR2) with colorectal cancer. METHODS AND RESULTS: Deoxyribonucleic...
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