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Article

Structural and molecular basis of interaction of HCV non-structural protein 5A with human casein kinase 1α and PKR.

BMC structural biology - 13 Nov 2012

Sudha Govindarajan, Yamunadevi Subburaj, Tyagi Nidhi, Das Saumitra, Srinivasan Narayanaswamy

Abstract excerpt

BACKGROUND: Interaction of non-structural protein 5A (NS5A) of Hepatitis C virus (HCV) with human kinases namely, casein kinase 1α (ck1α) and protein kinase R (PKR) have different functional implications such as regulation of viral replication and evasion of interferon induced immune response respectively. Understanding the structural and molecular basis of interactions of the viral protein with two different...

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Identifiers

PMID: 23148689
DOI: 10.1186/1472-6807-12-28
PMCID: PMC3534215

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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