Article
Novel Prognostic and Therapeutic Mutations in Acute Myeloid Leukemia.
Cancer genomics & proteomics - 1 Jan 2000
Medinger Michael, Lengerke Claudia, Passweg Jakob
Abstract excerpt
Acute myeloid leukemia (AML) is a biologically complex and molecularly and clinically heterogeneous disease, and its incidence increases with age. Cytogenetics and mutation testing remain important prognostic tools for treatment after induction therapy. The post-induction treatment is dependent on risk stratification. Despite rapid advances in determination of gene mutations involved in the pathophysiology and...
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