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Article

ANKHD1 regulates cell cycle progression and proliferation in multiple myeloma cells

6 Nov 2012

Abstract excerpt

ANKHD1 is a multiple ankyrin repeat containing protein, highly expressed in cancers, such as acute leukemia. The present study was undertaken to determine the expression and functional significance of ANKHD1 in human Multiple Myeloma (MM). We found that ANKHD1 is highly expressed in MM patient cells and cell lines. In vitro, lentiviral mediated ANKHD1-shRNA inhibited proliferation and delayed S to G2M cell cycle...

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PMID: 23142581
DOI: 10.1016/j.febslet.2012.10.037

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