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Article

Inhibition of DEPDC1A, a bad prognostic marker in multiple myeloma, delays growth and induces mature plasma cell markers in malignant plasma cells.

PloS one - 1 Jan 2013

Kassambara Alboukadel, Schoenhals Matthieu, Moreaux Jérôme, Veyrune Jean-Luc, Rème Thierry, Goldschmidt Hartmut, Hose Dirk, Klein Bernard

Abstract excerpt

High throughput DNA microarray has made it possible to outline genes whose expression in malignant plasma cells is associated with short overall survival of patients with Multiple Myeloma (MM). A further step is to elucidate the mechanisms encoded by these genes yielding to drug resistance and/or patients' short survival. We focus here on the biological role of the DEP (for Disheveled, EGL-10, Pleckstrin) domain...

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Source

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Identifiers

PMID: 23646139
DOI: 10.1371/journal.pone.0062752
PMCID: PMC3640027

Genes

CXCR4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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