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Article

Exploring the genetic architecture of circulating 25-hydroxyvitamin D.

Genetic epidemiology - 1 Jan 2013

Hiraki Linda T, Major Jacqueline M, Chen Constance, Cornelis Marilyn C, Hunter David J, Rimm Eric B, Simon Kelly C, Weinstein Stephanie J, Purdue Mark P, Yu Kai, Albanes Demetrius, Kraft Peter

Abstract excerpt

The primary circulating form of vitamin D is 25-hydroxy vitamin D (25(OH)D), a modifiable trait linked with a growing number of chronic diseases. In addition to environmental determinants of 25(OH)D, including dietary sources and skin ultraviolet B (UVB) exposure, twin- and family-based studies s...

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Identifiers

PMID: 23135809
DOI: 10.1002/gepi.21694
PMCID: PMC3524394

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23135809-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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Genome-wide association study identifies 143 loci associated with 25 hydroxyvitamin D concentration.Semantic proximity Read ↗

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Multi-ethnic analysis shows genetic risk and environmental predictors interact to influence 25(OH)D concentration and optimal vitamin D intakeSemantic proximity Read ↗

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