Article
Multi-ethnic analysis shows genetic risk and environmental predictors interact to influence 25(OH)D concentration and optimal vitamin D intake.
Genetic epidemiology - 1 Mar 2020
Hatchell Kathryn E, Lu Qiongshi, Mares Julie A, Michos Erin D, Wood Alexis C, Engelman Corinne D
Abstract excerpt
25-Hydroxyvitamin D (25(OH)D) concentration is a complex trait with genetic and environmental predictors that may determine how much vitamin D exposure is required to reach optimal concentration. Interactions between continuous measures of a polygenic score (PGS) and vitamin D intake (PGS*intake) or available ultraviolet (UV) radiation (PGS*UV) were evaluated in individuals of African (n = 1,099) or European...
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