Article
Genome-wide Association Study for Vitamin D Levels Reveals 69 Independent Loci.
American journal of human genetics - 5 Mar 2020
Manousaki Despoina, Mitchell Ruth, Dudding Tom, Haworth Simon, Harroud Adil, Forgetta Vincenzo, Shah Rupal L, Luan Jian'an, Langenberg Claudia, Timpson Nicholas J, Richards J Brent
Abstract excerpt
We aimed to increase our understanding of the genetic determinants of vitamin D levels by undertaking a large-scale genome-wide association study (GWAS) of serum 25 hydroxyvitamin D (25OHD). To do so, we used imputed genotypes from 401,460 white British UK Biobank participants with available 25OHD levels, retaining single-nucleotide polymorphisms (SNPs) with minor allele frequency (MAF) > 0.1% and imputation...
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