Article
Phenotypic characterization of the transgenic mouse insertional mutation, legless.
The Journal of experimental zoology - 1 Feb 1990
McNeish J D, Thayer J, Walling K, Sulik K K, Potter S S, Scott W J
Abstract excerpt
In this report, we describe the dysmorphologic phenotype associated with the transgenic insertional mutation legless. This autosomal recessive, perinatally lethal mutation results in an interesting pleiotropic array of congenital malformations. The phenotype of the legless mutation in homozygous...
Topics
- Animals
- Bone and Bones
- Crosses, Genetic
- DNA
- Facial Bones
- Genotype
- Limb Deformities, Congenital
- Mice
- Mice, Transgenic
- Microinjections
- Mutation
- Phenotype
- Skull
- Transformation, Genetic
- Viscera