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Article

Nucleotide composition of cellular internal ribosome entry sites defines dependence on NF45 and predicts a posttranscriptional mitotic regulon.

Molecular and cellular biology - 1 Jan 2013

Faye Mame Daro, Graber Tyson E, Liu Peng, Thakor Nehal, Baird Stephen D, Durie Danielle, Holcik Martin

Abstract excerpt

The vast majority of cellular mRNAs initiate their translations through a well-defined mechanism of ribosome recruitment that occurs at the 5'-terminal 7-methylguanosine cap with the help of several canonical protein factors. A subset of cellular and viral mRNAs contain regulatory motifs in their 5' untranslated regions (UTRs), termed internal ribosome entry sites (IRES), that sidestep this canonical mode of...

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Identifiers

PMID: 23129811
DOI: 10.1128/MCB.00546-12
PMCID: PMC3554113

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XIAP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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