Article
Germline mutations in RAD51C in Jewish high cancer risk families.
Breast cancer research and treatment - 1 Dec 2012
Kushnir Anya, Laitman Yael, Shimon Shani Paluch, Berger Raanan, Friedman Eitan
Abstract excerpt
Germline mutations in BRCA1 and BRCA2 account for ~30 % of inherited breast cancer. RAD51C was reported as an additional breast/ovarian cancer susceptibility gene in some populations. There is a paucity of data on the putative contribution of this gene to inherited breast/ovarian cancer in Jewish high risk families. High risk Jewish women, none of whom was a carrier of the predominant Jewish mutations in BRCA1 or...
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