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Identification and Characterization of the First Cholesterol-Dependent Cytolysins from Gram-Negative Bacteria

1 Nov 2012

Abstract excerpt

The cholesterol-dependent cytolysins (CDCs) are pore-forming toxins that have been exclusively associated with a wide variety of bacterial pathogens and opportunistic pathogens from the Firmicutes and Actinobacteria, which exhibit a Gram-positive type of cell structure. We have characterized the first CDCs from Gram-negative bacterial species, which include Desulfobulbus propionicus type species Widdel 1981 (DSM...

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PMID: 23115036
DOI: 10.1128/iai.00927-12

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