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Article

Frequency and clinicopathological characteristics of presenilin 1 Gly206Ala mutation in Puerto Rican Hispanics with dementia.

Journal of Alzheimer's disease : JAD - 1 Jan 2013

Arnold Steven E, Vega Irving E, Karlawish Jason H, Wolk David A, Nunez Jessica, Negron Mirna, Xie Sharon X, Wang Li-San, Dubroff Jacob G, McCarty-Wood Elisabeth, Trojanowski John Q, Van Deerlin Vivianna

Abstract excerpt

The frequency and clinical and pathological characteristics associated with the Gly206Ala presenilin 1 (PSEN1) mutation in Puerto Rican and non-Puerto Rican Hispanics were evaluated at the University of Pennsylvania's Alzheimer's Disease Center. DNAs from all cohort subjects were genotyped for the Gly206Ala PSEN1 mutation. Carriers and non-carriers with neurodegenerative disease dementias were compared for...

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Source

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Identifiers

PMID: 23114514
DOI: 10.3233/JAD-2012-121570
PMCID: PMC3575080

Genes

PSEN1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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