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Article

Presenilin 1 mutation in an african american family presenting with atypical Alzheimer dementia.

Archives of neurology - 1 Jun 2003

Rippon Gregory A, Crook Richard, Baker Matthew, Halvorsen Elizabeth, Chin Steven, Hutton Michael, Houlden Henry, Hardy John, Lynch Timothy

Abstract excerpt

BACKGROUND: Alzheimer disease (AD) is characterized by memory and visuospatial deficits with relative sparing of personality. Mutations in 3 genes (presenilin 1 and 2 and amyloid precursor protein) are associated with presenile AD. Presenilin 1 gene mutations have not been described in African Am...

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PMID: 12810495
DOI: 10.1001/archneur.60.6.884

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-12810495-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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